The high school football regular season is nearing its conclusion and playoff positioning is at stake. Here are the matchups for Week 8. Check back between 10 p.m. and 11 p.m. Friday as the scoreboard fills in.
Organized alphabetically by home team
| Thursday | |
| CBC 20 | Cardinal Ritter 30 (Thu) |
| St. Charles West 37 | Winfield 14 (Thu) |
| Friday | |
| Cuba (3-4) | Bayless (2-5) |
| Lutheran St. Charles (1-6) | Borgia (4-3) |
| Lift for Life (2-5) | Chaminade (4-3) |
| Miller Career 0 | Excelsior Springs 13 (forfeit win) |
| Hillsboro (6-1) | Farmington (6-1) |
| Riverview Gardens (3-4) | Fox (3-4) |
| Fort Zumwalt West (3-4) | Francis Howell Central (3-4) |
| Timberland (6-1) | Ft. Zumwalt East (3-4) |
| North Point (1-6) | Ft. Zumwalt South (1-6) |
| St. Vincent (6-1) | Grandview (0-7) |
| Jackson (7-0) | Hannibal (3-4) |
| Pacific (1-6) | Hermann (1-6) |
| Orchard Farm (5-2) | Holt (3-4) |
| Ste. Genevieve (5-2) | Jefferson (5-2) |
| McCluer (3-4) | Jennings (2-5) |
| Summit (4-3) | Kirkwood (5-1) |
| Eureka (5-2) | Lafayette (3-4) |
| Marquette (4-3) | Lindbergh (3-4) |
| Crystal City (1-6) | Malden (1-6) |
| Oakville (6-1) | Mehlville (0-7) |
| Wright City (3-4) | Montgomery County (4-3) |
| St. Clair (6-1) | North County (3-4) |
| Webster Groves (3-3) | Northwest Cedar Hill (6-1) |
| St. James (2-5) | Owensville (0-7) |
| Ladue (7-0) | Parkway Central (0-7) |
| McCluer North (5-2) | Parkway South (4-3) |
| Hazelwood West (2-5) | Parkway West (5-2) |
| Parkway North (3-4) | Pattonville (6-1) |
| Festus (5-2) | Poplar Bluff (1-6) |
| Lutheran South (1-6) | Portageville (5-2) |
| De Soto (3-4) | Potosi (3-4) |
| Hickman (5-2) | Rock Bridge (5-2) |
| Ritenour (5-2) | Seckman (6-1) |
| Gateway (3-3) | SLUH (5-2) |
| Warrenton (4-3) | St. Charles (2-5) |
| MICDS (5-2) | St. Dominic (4-3) |
| De Smet (6-1) | St. Mary’s (5-2) |
| Lutheran North (3-3) | St. Pius X-Kansas City (5-2) |
| Pembroke Hill (7-0) | Summit Christian (6-1) |
| Liberty (Wentzville) (2-5) | Troy Buchanan (6-1) |
| Sullivan (5-2) | Union (6-1) |
| Affton (3-4) | University City (7-0) |
| Saxony Lutheran (4-2) | Valle Catholic (7-0) |
| John Burroughs (2-3) | Veritas Christian (3-2) |
| St. Pius X (Festus) (5-2) | Vianney (2-5) |
| Ft. Zumwalt North (4-2) | Washington (2-5) |
| Fredericktown (2-5) | Windsor (2-5) |
| Saturday | |
| Normandy (3-4) | Clayton (0-7) |
| Hazelwood East (0-7) | Hazelwood Central (1-6) |
| Herculaneum (4-3) | Perryville (3-4) |
| Kelly (4-3) | Principia (2-4) |
| Confluence (0-6) | Priory (2-5) |
| Duchesne (3-4) | Westminster (5-2) |